Fate of antigen after intravenous and intraarticular injection into rabbits
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چکیده
منابع مشابه
Pharmacokinetics of m-nifedipine in rabbits after intravenous injection.
AIM To study the dose effects on pharmacokinetics of m-Nif. METHODS Fifteen rabbits were divided into 3 groups receiving i.v. m-Nif 0.5, 1, and 2 mg.kg-1. Plasma levels of m-Nif were determined with HPLC method. RESULTS The concentration-time data were fitted with 2-compartment model. After i.v. 1 mg.kg-1, the parameters were: Vd = 0.37 +/- 0.10 L.kg-1, T1/2 alpha = 6.4 +/- 2.9 min, T1/2 be...
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Pharmacokinetic studies of GdDTPA/dimeglumine in man show a rapid renal clearance and no evidence for dissociation or retention of the complex in the body. These features, in conjunction with its strong proton relaxation enhancement and its low toxicity suggest that this complex may be an excellent contrast medium for magnetic resonance imaging.
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1978
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780210808